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The interaction of proteins with hydroxyapatite: I. Role of protein charge and structure

✍ Scribed by Marina J. Gorbunoff

Book ID
107712014
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
661 KB
Volume
136
Category
Article
ISSN
0003-2697

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πŸ“œ SIMILAR VOLUMES

The interaction of proteins with hydroxy
The interaction of proteins with hydroxyapatite: II. Role of acidic and basic groups
✍ Marina J. Gorbunoff πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 English βš– 542 KB

The elution behavior from hydroxyapatite columns of the modification products of seven basic and three acidic proteins has been investigated. Three classes of NH2 derivatives were prepared. These consisted of (1) replacement by a guanidyl group with no change in charge; (2) blocking with loss of cha

The interaction of proteins with hydroxy
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The mechanism of protein binding to and elution from hydroxyapatite (HA) has been established. Binding occurs both by nonspecific attraction between protein positive charges and HA and by specific complexing of protein carboxyls with calcium loci on the mineral. Elution can take place either as the

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