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The interaction of hedamycin and DC92-B in a sequence selective manner with DNA in intact human cells

โœ Scribed by Vincent Murray; Anthony G. Moore; Christina Matias; Geoffrey Wickham

Book ID
113263066
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
784 KB
Volume
1261
Category
Article
ISSN
0167-4781

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## Abstract The effect of two different DNA minor groove binding molecules, Hoechst 33258 and distamycin A, on the binding kinetics of NFโ€ฮบB p50 to three different specific DNA sequences was studied at various salt concentrations. Distamycin A was shown to significantly increase the dissociation ra