The interaction of cobalt(II) complexes with bovine apocarbonic anhydrase B

✍ Scribed by K. Gerber; F.T.T. Ng; R.G. Wilkins

• Publisher: Elsevier Science
• Year: 1975
• Weight: 544 KB
• Volume: 4
• Category: Article
• ISSN: 0006-3061
• DOI: 10.1016/s0006-3061(00)81024-8

✦ Synopsis

The second-order rate constants for interaction of a number of cobalt(H) complexes (including the aquated ion) with bovine apocarbonic anhydrase have been measured at pH = 7.5, 25°C and I = 0.1 M. The ease of entry of cobalt decreases, in general, as the number of its coordinated waters decreases. The highest complexes (bis or tris) do not react. The Mono cobalt(H)-8quinolinol-5-sulfonate and, particularly, 8quinolinol complexes react very much more rapidly with apoenzyme than does CO(H=O)~** ion The results are discussed.