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The interaction of chemically modified human plasma α1-antitrypsin with porcine pancreatic elastase

✍ Scribed by James C. Fretz; Jose C. Gan


Book ID
115703821
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
181 KB
Volume
188
Category
Article
ISSN
0003-9861

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✍ Ines Li de la Sierra; Emmanuel Papamichael; Constantinos Sakarellos; Jean-Luc Di 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 880 KB

## Abstract The peptide trifluoroacetyl‐Leu‐Ala‐(__p__‐trifluoromethylanilide), is a reversible inhibitor of pancreatic porcine elastase and is characterized by a __K__~m~ of 2.5 × 10^−8^ M. Co‐crystals of the 1:1 complex were obtained in an acetate buffer + dimethylformamide solution at pH 5.7. Di