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The interaction of biological molecules with heparin and related glycosaminoglycans. 1. Identification of a specific heparin binding site for histamine

✍ Scribed by Rabenstein, Dallas L.; Bratt, Peter; Schierling, Timothy D.; Robert, Jan M.; Guo, Wei


Book ID
127029724
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
991 KB
Volume
114
Category
Article
ISSN
0002-7863

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Identification of a heparin binding site
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The carboxy-terminal globular domain (G-domain) of the laminin ␣1 chain has been shown to promote heparin binding, cell adhesion, and neurite outgrowth. In this study, we defined the potential sequences originating from the G-domain of laminin ␣1 chain which possess these functional activities. A se