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The interaction of adriamycin and adriamycin analogues with nucleic acids in the B and A conformations

โœ Scribed by Terence W. Plumbridge; Jeffrey R. Brown


Book ID
115747122
Publisher
Elsevier Science
Year
1979
Weight
800 KB
Volume
563
Category
Article
ISSN
0005-2787

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โœ Michael Petersen; Christina B. Nielsen; Katrine E. Nielsen; Gitte A. Jensen; Ken ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 973 KB

We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide as well as three 9-and 10-mer modified oligonucleo