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The interaction between the membrane-proximal external region and the N-trimer region of HIV-1 gp41: Involvement in viral fusion

โœ Scribed by Li, Jing ;Lu, Lu ;Wu, Fan ;Chen, Xi ;Niu, Ben ;Jiang, ShiBo ;Chen, YingHua


Book ID
107368956
Publisher
Elsevier
Year
2009
Tongue
English
Weight
660 KB
Volume
54
Category
Article
ISSN
2095-9273

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## Abstract The membrane proximal external region (MPER) of gp41 abuts the viral membrane at the base of HIVโ€1 envelope glycoprotein spikes. The MPER is highly conserved and is rich in Trp and other lipophilic residues. The MPER is also required for the infection of host cells by HIVโ€1 and is the t