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The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines

✍ Scribed by Dennis E .Hallahan; Michael A. Beckett; Donald Kufe; Ralph R. Weichselbaum

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
725 KB
Volume
19
Category
Article
ISSN
0360-3016

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The ability of recombinant human tumor necrosis factor (rH-TNF-alpha) to induce regression of sarcoma 180 in vivo was evaluated. The tumor was cured by TNF in the course of 4 weeks. TNF inhibited proliferation of sarcoma 180 cells in vitro, which suggests a direct effect of TNF on tumor cells in viv