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The interaction between prostaglandin E1andΔ9-Tetrahydrocannabinol on intestinal motility and on the abdominal constriction response in the mouse

✍ Scribed by D. M. Jackson; R. Malor; G. B. Chesher; G. A. Starmer; P. J. Welburn; Ruth Bailey

Publisher
Springer
Year
1976
Tongue
English
Weight
645 KB
Volume
47
Category
Article
ISSN
0033-3158

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Tolerance to the effects ofΔ9-tetrahydro
Tolerance to the effects ofΔ9-tetrahydrocannabinol in mice on intestinal motility, temperature and locomotor activity
✍ Pamela F. Anderson; D. M. Jackson; G. B. Chesher; R. Malor 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 558 KB

The onset and duration of tolerance to three effects of A9-tetrahydrocannabinol (A9-THC) given orally to mice were compared. The effects of A9-THC studied were: hypothermia, the depression of intestinal motility and the effect on spontaneous locomotor activity. When mice were dosed and tested at 24