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The integration of signaling by multiprotein complexes containing Raf kinases

✍ Scribed by John M. Kyriakis


Book ID
113486026
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
374 KB
Volume
1773
Category
Article
ISSN
0167-4889

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Cell proliferation in response to growth factors is mediated by specific high affinity receptors. Ligand-binding by receptors of the protein tyrosine kinase family results in the stimulation of several intracellular signal transduction pathways. Key signalling enzymes are recruited to the plasma mem