✦ LIBER ✦

The insecticidal activity of derivatives of the ionophore X-206

✍ Scribed by Fiebich, Katrin; Hoermann, Aldo; Mutz, Michael; O'Sullivan, Anthony C; Rindlisbacher, Alfred; Struber, Fritz

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 151 KB
Volume: 55
Category: Article
ISSN: 1526-498X
DOI: 10.1002/(sici)1096-9063(199903)55:3<379::aid-ps919>3.0.co;2-m

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✦ Synopsis

The naturally-occurring ionophore X206, originally isolated for its antibacterial activity, also exhibits broad insecticidal and acaricidal activity. This summary reports structure/activity studies with X206 and 34 derivatives as well as mode of action studies. Although many compounds showed promising insecticidal activity, it was only of a contact activity nature ; furthermore, the acute LD 50 of the compounds in rats precluded further development of these compounds.

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