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The initiation site for recombination cog is at the 3′ end of the his-3 gene in Neurospora crassa

✍ Scribed by Bowring, Frederick J. ;Catcheside, David E. A.

Publisher
Springer
Year
1991
Tongue
English
Weight
527 KB
Volume
229
Category
Article
ISSN
0026-8925

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✦ Synopsis

Recombination at his-3 in Neurospora crassa is thought to be initiated through a site designated cog which lies in the his-3 to ad-3 interval of linkage group I. Fragments of the his-3 gene were used to transform various his-3 mutant alleles to prototrophy in order to link the genetic map to the nucleotide sequence. It was established that cog is at the 3' end of his-3 and is therefore not the his-3 promoter. This suggests that cog may be dissimilar to a number of yeast recombinators which are associated with promoters of transcription.

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