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The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

✍ Scribed by Peter van Lent; Karin C. Nabbe; Peter Boross; Arjen B. Blom; Johannes Roth; Astrid Holthuysen; Annet Sloetjes; Sjef Verbeek; Wim van den Berg

Book ID: 117021714
Publisher: American Society for Investigative Pathology
Year: 2003
Tongue: English
Weight: 732 KB
Volume: 163
Category: Article
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)63543-2

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## Objective: To study the role of the activating fc gamma receptor types i and iii (fc gamma ri and fc gamma riii, respectively) and the inhibiting fc gamma receptor ii (fc gamma rii) in inflammation and in various aspects of cartilage destruction during arthritis that is solely induced by immune