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The inhibitory effects of PKCθ on adiponectin expression is mediated by ERK in 3T3-L1 adipocytes

✍ Scribed by Sun, S.; Liu, Y.; Lu, J.; Omar, A.; Sun, S.; Bi, Y.; Wang, C.

Book ID
125336945
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
864 KB
Volume
34
Category
Article
ISSN
0391-4097

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## Abstract PPARγ plays a key role in adipocyte specific gene expression. In this study, we assessed the effects of phorbol ester (TPA)‐sensitive PKC (c/nPKC) activation on the expression of adipocyte specific genes and inflammation related genes. Treatment with both TPA and TNFα decreased mRNA lev