This study was designed to test the chemopreventive potential of perillyl alcohol, an inhibitor of farnesyltransferase, in a mouse lung tumor bioassay. Perillyl alcohol is a naturally occurring monoterpene found in lavender, cherries, and mint. We have shown previously that the majority of lung tumo
✦ LIBER ✦
The inhibitory effect of vitamin E on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA injury and the fixation of the DNA injury in mouse lungs
✍ Scribed by T. Yano; Shoko Yajima; Toshihiro Nakamura; Saburo Horikawa; Mikako Kishimoto; Tomio Ichikawa
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 70 KB
- Volume
- 358
- Category
- Article
- ISSN
- 0028-1298
No coin nor oath required. For personal study only.
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## Abstract ChrCrx (6‐hydroxy‐2, 5, 7, 8‐tetramethyl‐chroman‐2‐carboxylic acid) is a water‐soluble analog in which 4′, 8′, 12′‐trimethyltridecyl chain is deleted from an alpha‐tocopherol molecule known as a hydrophobic antioxidant. Cell viability of human skin epidermal keratinocytes HaCaT was lowe