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The inhibitor profiling of the caspase family of proteases using substrate-derived peptide glyoxals

✍ Scribed by Diarmaid J. Murphy; Brian Walker; Ciara A. Ryan; S. Lorraine Martin


Book ID
116300968
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
557 KB
Volume
402
Category
Article
ISSN
0006-291X

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Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cmdc.201000395. Scheme 1. a) HCl, MeOH; b) Et 3 N, 4-CO 2 MePhSO 2 Cl, CH 2 Cl 2 ; c) DEAD, Ph 3 P, iso-amyl alcohol, THF; d) LiBH 4 , THF; e) TBDPS-Cl, imidazole, CH 2 Cl 2 ; f) H 2 , Pd(OH) 2 , MeOH; g)