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The Inhibition of the Mitochondrial NADH Oxidase by Alprenolol and the Protective Effect of Cytochrome P-450

✍ Scribed by Grundin, Robert ;Thor, Hjördis ;Orrenius, Sten

Book ID: 114799119
Publisher: Wiley (Blackwell Publishing)
Year: 2009
Weight: 483 KB
Volume: 37
Category: Article
ISSN: 0001-6683
DOI: 10.1111/j.1600-0773.1975.tb00832.x

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## Abstract Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In addition, nonspecific Cu^2+^‐binding to thiol enzymes, which modifi