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The inhibition of rabies virus by arabinosyl cytosine. Studies on the mechanism and specificity of action

โœ Scribed by Campbell, James B.; Maes, Roland F.; Wiktor, Tadeusz J.; Koprowski, Hilary

Book ID
122001369
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
677 KB
Volume
34
Category
Article
ISSN
0042-6822

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We have demonstrated that Ara-C incorporates in leukemic cell DNA and that the extent of this incorporation correlates significantly with loss of clonogenic survival. This relationship between formation of (Ara-C)DNA and cytotoxicity is also obtained in the presence of modulating agents such as thym