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The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid

✍ Scribed by KHWAJA, ARIF; SHARPE, CLAIRE C; NOOR, MAZHAR; KLOOG, YOEL; HENDRY, BRUCE M


Book ID
109067229
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
217 KB
Volume
68
Category
Article
ISSN
0085-2538

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## Abstract The present study examined the effects of all‐__trans__ retinoic acid (tRA) on proliferation and expression of the IGF system in Caco‐2 human colon adenocarcinoma cells. tRA inhibited Caco‐2 cell proliferation in a dose‐dependent manner, with a 40 ± 2% decrease in cell number observed 4