𝔖 Bobbio Scriptorium
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The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action

✍ Scribed by Robert Jarzyna; Anna Kiersztan; Olesia Lisowa; Jadwiga Bryła

Book ID
114014154
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
91 KB
Volume
428
Category
Article
ISSN
0014-2999

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## Abstract Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti‐tumor activity against many tumor cell lines. But the mechanisms through which OA inhibits osteosarcoma cells are not known. The mammalian target of rapamycin (mTOR) serves as a central regulator of cell growth, prolif