The inheritance of a defective lipopolysaccharide response locus in C3H/HeJ mice
β Scribed by Kathleen Kelly; James Watson
- Publisher
- Springer-Verlag
- Year
- 1977
- Tongue
- English
- Weight
- 525 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0093-7711
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π SIMILAR VOLUMES
## Abstract Mice of the C3H/HeJ strain exhibit low inflammatory and immunological responses to certain bacterial lipopolysaccharide (LPS) preparations. Lymphocytes from C3H/HeJ mice also show defective LPSβinduced mitogenesis. We tested the colony stimulating activity (CSA) response of C3H/HeJ mice
## The IgM anti-lipopolysaccharide response in mice" Mice of different genotypes were immunized with Salmonella anatum. The cross-reactivity patterns of their IgM anti-S. anatum lipopolysaccharide (LPSAN) antibodies were characterized by their relative avidity toward heterologous LPS. When the LP