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The influence of the branched-chain fatty acids pristanic acid and Refsum disease-associated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes

✍ Scribed by Sabine Rönicke; Nicol Kruska; Stefan Kahlert; Georg Reiser


Book ID
113812391
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
900 KB
Volume
36
Category
Article
ISSN
0969-9961

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Phytanic acid and pristanic acid, branch
✍ Nicol Kruska; Georg Reiser 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 824 KB

The accumulation of the two branched-chain fatty acids phytanic acid and pristanic acid is known to play an important role in several diseases with peroxisomal impairment, like Refsum disease, Zellweger syndrome and α-methylacyl-CoA racemase deficiency. Recent studies elucidated that the toxic activ