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The influence of removal of primary tumor on incidence and phenotype of circulating tumor cells in primary breast cancer

✍ Scribed by Malgorzata Banys; Natalia Krawczyk; Sven Becker; Jolanta Jakubowska; Annette Staebler; Diethelm Wallwiener; Tanja Fehm; Ralf Rothmund

Publisher: Springer US
Year: 2011
Tongue: English
Weight: 300 KB
Volume: 132
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-011-1569-0

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## Abstract Abnormal DNA methylation is a feature of most types of cancer, which is reflected in cell‐free circulating DNA in plasma. It is, however, unknown whether surgical removal of the tumor and subsequent therapy induces changes in plasma DNA methylation, which can be used to monitor treatmen