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The influence of regulatory T cells and diurnal hormone rhythms on T helper cell activity

✍ Scribed by Thomas Bollinger; Annalena Bollinger; Julius Naujoks; Tanja Lange; Werner Solbach

Book ID
108782788
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
433 KB
Volume
131
Category
Article
ISSN
0019-2805

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## Abstract Autoimmunity is thought to reflect an imbalance between regulatory T helper lymphocytes (Treg) and pathogenic, IL‐17‐secreting T helper (Th17) cells. Induction of both adaptive Treg and Th17 cells requires signalling from TGF‐β. We now show that, in the context of TGF‐β signalling, all‐