The Influence of Recombinant Human Erythropoietin on Apoptosis and Cytokine Production of CD4+lymphocytes from Hemodialyzed Patients
✍ Scribed by Katarzyna A. Lisowska, Alicja Dębska-Ślizień…
- Book ID
- 120691647
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 253 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0271-9142
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The production of recombinant proteins by mammalian cells demands a highly controlled environment for cell cultivation. Temperature stress represents a commonly encountered disturbance in both research and process environments. In this study, we examined the effects of heat shock on the expression o
## Abstract Human recombinant erythropoietin (rHuEPO) was produced from Chinese hamster ovary (CHO) cells transfected with the human EPO gene. The cells were grown in batch cultures in controlled bioreactors in which the set‐points for dissolved oxygen varied between 3% and 200%. The cell‐specific