The influence of proline residues on α-helical structure
✍ Scribed by Derek N. Woolfson; Dudley H. Williams
- Book ID
- 115923650
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 358 KB
- Volume
- 277
- Category
- Article
- ISSN
- 0014-5793
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## Abstract Mutations in desmin gene have been identified in patients with cardiac and skeletal myopathy characterized by intracytoplasmic accumulation of desmin‐reactive deposits and electron‐dense granular aggregates. We characterized two new desminopathy families with unusual features of adult‐o
The proline residues in proteins are known to play an important structural role. Recently, the role of a proline residue in the middle of right-handed a-helical segments of peptides has been the focus of attention. This role seems to be particularly important in the case of membrane proteins and in