✦ LIBER ✦
The influence of preculture on the process performance of penicillin V production in a 100-l air-lift tower loop reactor
✍ Scribed by J. Möller; J. Niehoff; S. Hotop; M. Dors; K. Schügerl
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 544 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1432-0614
No coin nor oath required. For personal study only.
✦ Synopsis
The influence of stirrer speed in the third preculture on the performance of penicillin V production by Penicillium chrysogenum in complex medium in a 100-1 air-lift tower loop reactor was investigated. The process performance in the main culture was improved by increasing the stirrer speed from 500 to 750 rpm: the pellet size was reduced to half, the cell growth was influenced only slightly, but the production phase was extended considerably, and the final penicillin concentration was increased from 5.