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The influence of obidoxime, diacetylmonoxime, pralidoxime, and two less hydrophilic derivatives of pralidoxime upon the cholinesterase inhibition and the pressor effect by paraoxon in the rat

โœ Scribed by Joost H. de Neef; Arijan J. Porsius


Book ID
113205920
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
672 KB
Volume
66
Category
Article
ISSN
0041-008X

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## Abstract Intoxication with the organophosphorus compound paraoxon (POX), an inhibitor of serine hydrolases, is frequent. Although oximes are the only enzyme reactivators presently available, clinical experience with their use was rather disappointing. Recent work has shown that under certain con