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The Influence of Noncomplementary Bases on the Stability of Ordered Polynucleotides

โœ Scribed by E. K. F. Bautz and F. A. Bautz

Book ID
123657976
Publisher
National Academy of Sciences
Year
1964
Tongue
English
Weight
263 KB
Volume
52
Category
Article
ISSN
0027-8424

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The stability of the parallel-stranded (ps) DNA duplexes is increased when the dA-residues are replaced by the 7-substituted 7-deaza-2'-deoxyadenosine derivatives 3a,b or the dG-residues by the 8-aza-7-deazapurine 2'-deoxynucleosides 6 and 7a,b. Also the N-7-glycosylated adenine 5 forms stable base