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The influence of neuronal cells on the development of glutamine synthetase in astrocytes in vitro

✍ Scribed by Masao Hayashi; Ritsuko Hayashi; Hideji Tanii; Kazuo Hashimoto; Ambrish J. Patel


Book ID
119101466
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
513 KB
Volume
41
Category
Article
ISSN
0165-3806

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Cocultures of rat cortical astrocytes with cerebellar granule cell neurons, but not a variety of other cell types tested, resulted in an induction of glutamine synthetase (GS) mRNA over the basal levels expressed in pure astrocyte cultures. This induction involved both contact-and noncontact-mediate