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The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue

โœ Scribed by Paromov, Victor (author);Qui, Min (author);Yang, Hongsong (author);Smith, Milton (author);Stone, William L. (author)

Publisher
BioMed Central
Year
2008
Tongue
English
Weight
772 KB
Volume
9
Category
Article
ISSN
1471-2121

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The influence of N-acetyl-L-cysteine on
The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue
โœ Paromov, Victor (author);Qui, Min (author);Yang, Hongsong (author);Smith, Milton ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 772 KB

## Background Sulphur mustard gas, 2, 2'-dichlorodiethyl sulphide (HD), is a chemical warfare agent. Both mustard gas and its monofunctional analogue, 2-chloroethyl ethyl sulphide (CEES), are alkylating agents that react with and diminish cellular thiols and are highly toxic. Previously, we reporte