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The influence of mesenchymal stromal cells on B-cell line growth and immunoglobulin synthesis

✍ Scribed by M. P. Samoylovich, A. A. Pinevich, O. A. Shashkova…

Book ID
120951152
Publisher
Pleiades Publishing
Year
2013
Tongue
English
Weight
420 KB
Volume
7
Category
Article
ISSN
1990-519X

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Background aims. Culture medium for mesenchymal stromal cells (MSC) is frequently supplemented with fetal calf serum (FCS). FCS can induce xenogeneic immune reactions, transmit bovine pathogens and has a high lot-to-lot variability that hampers reproducibility of results. Several studies have demons