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The influence of low molecular weight heparin on the expression of osteogenic growth factors in human fracture healing

✍ Scribed by Kambiz Sarahrudi; Georg Kaiser; Anita Thomas; Mark Michel; Harald Wolf; Mehdi Mousavi; Seyedhossein Aharinejad


Book ID
113026981
Publisher
Springer
Year
2011
Tongue
English
Weight
156 KB
Volume
36
Category
Article
ISSN
0341-2695

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The purpose of this study was to evaluate the effect of low molecular weight heparin (LMWH) on fracture healing in a standard stabilized rat femur fracture model. A closed, mid-diaphyseal transverse fracture was created in the right femur of Long-Evans rats after insertion of a 0.8-mm K-wire into th

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During fracture healing, multipotential stem cells di!erentiate into specialized cells responsible for producing the di!erent tissues involved in the bone regeneration process. This cell di!erentiation has been shown to be regulated by locally expressed growth factors. The details of their regulator