The influence of fluid mixing upon respiratory patterns for extended growth of a methylotroph in an air-lift fermenter
✍ Scribed by Peter R. Fields; Nigel K. H. Slater
- Book ID
- 102766617
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 903 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0006-3592
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✦ Synopsis
Abstract
The influence of methanol dispersion and fluid mixing upon respiratory patterns observed during unlimited fedbatch growth of the methylotrophic bacterium Methylophilus methylotrophus has been investigated. A concentric tube air‐lift fermenter was employed for which the mixing and fluid circulation patterns have been well characterized. Respiratory quotients showed a marked dependence upon the position in the vessel at which methanol was injected, the volumetric rate of such methanol addition, the fluid circulation time, and the local mixing behavior; the latter two factors of which are both determined by the air throughput. Such variations are discussed on the basis of simple mixing concepts and observations of fluid dispersion.