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The influence of exercise on the neuromuscular activity of relaxant drugs

✍ Scribed by Francis F. Foldes; Almiro P. Monte; H. M. Brunn; Bernard Wolfson

Publisher
Springer-Verlag
Year
1961
Tongue
French
Weight
678 KB
Volume
8
Category
Article
ISSN
1496-8975

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The effect of variable protein binding (taken as independent parameter) on pharmacological activity of drugs is considered in terms of the exposure or the steady state concentration of unbound drug at targeted tissue. Based on the application of the parallel tube or dispersion models it is shown tha