The application of guidelines linked to the concept of drug-likeness, such as the 'rule of five', has gained wide acceptance as an approach to reduce attrition in drug discovery and development. However, despite this acceptance, analysis of recent trends reveals that the physical properties of molec
โฆ LIBER โฆ
The influence of drug-like concepts on decision-making in medicinal chemistry
โ Scribed by Leeson, Paul D.; Springthorpe, Brian
- Book ID
- 109950436
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 541 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1474-1776
- DOI
- 10.1038/nrd2445
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