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The influence of dose interval on the immunosuppressive potency of methylprednisolone: an experimental organ transplant study in isogenous rats

✍ Scribed by B. S. Husberg; P. I. Konrad

Book ID
115134004
Publisher
Springer
Year
1990
Tongue
English
Weight
296 KB
Volume
3
Category
Article
ISSN
0934-0874

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The influence of dose interval on the im
The influence of dose interval on the immunosuppressive potency of methylprednisolone: an experimental organ transplant study in isogenous rats
✍ B. S. Husberg; P. I. Konrad πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 300 KB

Groups of isogenous Brown-Norway rats received heterotopic heart transplants from (Brown-Norway/Wistar Furth) x F1 hybrid rats. Methylprednisolone was administered IV in a daily dose of 5-40 mg/kg, using a dose interval of 24, 12, or 0 h (continuous infusion). Continuous infusion proved to be superi

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Bile secretion is reduced after liver transplantation. It has been suggested that this is due either to the effect of cyclosporin or to the damage to the liver graft during preservation and reperfusion. The aim of this study was to explore the influence of cyclosporin as well as of liver transplanta