The influence of DNA base ratios on intragenic mutational spectra in prokaryotes
β Scribed by Colin H. Clarke
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 744 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To determine the influence of DNA repair by Ogt alkyltransferase. The Ogt protein appears more efalkyltransferase on the distribution of alkylnitro-ficient at repairing O 6 -ethylguanine lesions, which sourea-induced mutations, we have analysed in are flanked 5 by a G or C, in agreement with pre-Ogt
The expedient of preparing homologous DNA samples substituted with inosine for guanosine residues, 2,6-diaminopurine (DAP) for adenine residues, or both, has been used to investigate the role of the purine 2-amino group in determining the preferred binding sites for the drugs berenil [1,3-bis(4-phen
In the absence of nucleotide excision repair, the spectra were dominated by G:CrA:T transitions, additional deficiency of the DNA alkyltransferase consistent with the major role of the O 6 -alkylguanine (ATase) encoded by the constitutive ogt gene of miscoding lesion in mutagenesis by alkylating Esc