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The influence of Azone, propylene glycol and polyethylene glycol on in vitro skin penetration of trifluorothymidine

✍ Scribed by Sheth, Nitin V.; Freeman, Donna J.; Higuchi, William I.; Spruance, Spotswood L.

Book ID
123168446
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
919 KB
Volume
28
Category
Article
ISSN
0378-5173

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The mechanism underlying propylene glycol (PG) effects on acyclovir (ACV) penetration through human epidermis were studied. Solvent systems and Carbopol gels containing increasing percentage of PG (from 0% to 70%, w/w) were used. Viscosity studies of both vehicles were carried out to characterise th