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The influence of apomorphine and tricyclic antidepressant drugs on the level of serotonin and its metabolite in rat brain

✍ Scribed by Maria Grabowska; Lucyna Antkiewicz; Jerzy Michaluk

Book ID
115772572
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
397 KB
Volume
24
Category
Article
ISSN
0006-2952

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Because tricyclic antidepressants (TAD) are usually given chronically to patients, both their acute and their chronic effects on 5-hydroxytryptamine (5-HT) metabolism were studied. The probenecid method was used and, in addition to 5-hydroxy-indoleacetic acid (5-HIAA), some other indole compounds in