The influence of androgens, anti-androgens, and castration on cell proliferation in the jejunal and colonic crypt epithelia, and in dimethylhydrazine-induced adenocarcinoma of rat colon
โ Scribed by Tutton, P. J. M. ;Barkla, D. H.
- Publisher
- Springer-Verlag
- Year
- 1981
- Weight
- 277 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0042-6431
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In previous studies, N-(N'-acetyl-L-propyl)-N-nitrosoglycine (APNG) has been shown to be a potent mutagen in a variety of genotoxicity assays and a carcinogen in a limited cancer study. APNG decomposes to a carboxymethyldiazonium ion, which can also be generated from potassium diazoacetate (KDA). KD
## Abstract The regulatory role of estrogen on cell population kinetics in the descending colon was studied in intact female and ovariectomized mice. In the colonic crypts from intact mice, the crypt size (the number of epithelial cells per crypt column) and the proliferative activity of epithelial