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The influence of amitriptyline and carbamazepine on levomepromazine metabolism in human liver: An in vitro study

✍ Scribed by Wójcikowski, Jacek; Basińska, Agnieszka; Boksa, Jan; Daniel, Władysława A.

Book ID
126915640
Publisher
Elsevier
Year
2014
Tongue
English
Weight
603 KB
Volume
66
Category
Article
ISSN
1734-1140

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The metabolism of the tricyclic antidepressants amitriptyline (AMI), imipramine (IMI), chlorimipramine (CMI) and some of their metabolites was studied in vitro in isolated liver microsomes of female Spraque-Dawley rats. Nine metabolites of AMI, seven metabolites of IMI, and 11 metabolites of CMI wer