𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The induction of cytochrome P-450 in Lodderomyces elongisporus

✍ Scribed by Dipl.-Biochem. S. Mauersberger; W.-H. Schunck; H.-H. Müller

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
582 KB
Volume
21
Category
Article
ISSN
0233-111X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In the alkane‐utilizing yeast strain Lodderomyces elongisporus cytochrome P‐450 is induced by aliphatic hydrocarbons and to a lesser degree also by some of their derivatives. Cycloheximide and glucose inhibit the induction process, the former by inhibition of cytoplasmic translation, the latter presumably by catabolite repression. Among the nearly 40 checked compounds tetradecane and 1‐tetradecene are the most effective inducers. The branching of the alkyl chain as well as the terminal introduction of electrophilic atoms decrease the induction effect.

📜 SIMILAR VOLUMES

Mechanisms of cytochrome P450 induction
Mechanisms of cytochrome P450 induction
✍ Leslie M. Tompkins; Andrew D. Wallace 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

## Abstract Cytochrome P450s (CYPs) are important heme‐containing proteins that play important roles in the metabolism of xenobiotics and endogenous compounds. The oxidative metabolisms of drugs, environmental chemicals, hormones, and fatty acids by CYP enzymes are critical pathways aiding in their

The induction of cytochrome P450 1A1 by
The induction of cytochrome P450 1A1 by Sudan Dyes
✍ Nahla A. G. Ahmed Refat; Zein Shaban Ibrahim; Gihan Gamal Moustafa; Kentaro Q. S 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 320 KB

## Abstract Azo dyes form a major class of chemically related compounds that are ubiquitous in foods, paints, printing inks, cosmetics, and also used as biological stains in histological and histopathological laboratories and clinics. Sudan I, sudan III, and sudan IV have been classified as categor

The roles of cytochrome b5 in cytochrome
The roles of cytochrome b5 in cytochrome P450 reactions
✍ Todd D. Porter 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB

## Abstract Cytochrome __b__~5~, a 17‐kDa hemeprotein associated primarily with the endoplasmic reticulum of eukaryotic cells, has long been known to augment some cytochrome P450 monooxygenase reactions, but the mechanism of stimulation has remained controversial. Studies in recent years have clari

Adult specific expression and induction
Adult specific expression and induction of cytochrome P450tpr in house flies
✍ Jeffrey G. Scott; Padma Sridhar; Nannan Liu 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 681 KB

Cytochrome P450,,, is a xenobiotic metabolizing P450 that is found i n house flies (Musca dornestica). To better understand the regulation of cytochrorne P450,,,, the effects of 21 potential monooxygenase inducers were examined for their ability to induce total cytvchromes P450 and cytochrome P450,,