H2O2 induces upregulation of Fas and Fas
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F. Facchinetti; S. Furegato; S. Terrazzino; A. Leon
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Article
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2002
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John Wiley and Sons
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English
โ 415 KB
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Fas, (APO-1/CD95), a transmembrane glycoprotein belonging to the tumor necrosis (TNF) receptor superfamily, transduces apoptotic death upon crosslinking by its cognate ligand (FasL). As upregulation of Fas/FasL expression occurs in neuropathological conditions (e.g., stroke, central nervous system [