✦ LIBER ✦

The inclusion of double-channel ultraviolet spectrophotometry in an expert system for pharmaceutical analysis

✍ Scribed by J. Smeyers-Verbeke; M.R. Detaevernier; D.L. Massart

Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 716 KB
Volume: 191
Category: Article
ISSN: 0003-2670
DOI: 10.1016/s0003-2670(00)86307-2

No coin nor oath required. For personal study only.

✦ Synopsis

Different criteria are compared for the selection of optimal wavelengths in the U.V. spectrophotometry of pharmaceutical samples. The effect of over-determination on the precision and accuracy of the results is evaluated. It is concluded that for the commercial samples of tablets containing two active substances investigated, good results are obtained when the classical approach (measurement at A,, ) is applied and that no improvement is observed when over-determination is used. Rules are derived to include the two-component U.V. spectrophotometry in an expert system for pharmaceutical analysis.

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