Advantage of using CBA/N strain mice in
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Masahiro Takeyoshi; Shuji Noda; Kanji Yamasaki; Ian Kimber
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Article
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2005
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John Wiley and Sons
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English
โ 144 KB
The murine local lymph node assay (LLNA) is currently recognized as a stand-alone test method for determining the skin sensitizing potential of chemicals. It has been incorporated into the official test guidelines published by some authorities, including the OECD. To avoid the use of radioisotopes,