Anticipation in bipolar affective disord
✍
Alda, M. ;Grof, P. ;Ravindran, L. ;Cavazzoni, P. ;Duffy, A. ;Grof, E. ;Zvolsk�,
📂
Article
📅
2000
🏛
John Wiley and Sons
🌐
English
⚖ 71 KB
Anticipation has been suggested among the genetic mechanisms of bipolar disorder (BD), prompting the search for unstable DNA sequences. Past studies of anticipation in BD have generally relied on observed shift in the age at onset between parental and offspring generations. Such a shift, however, ma