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The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel

✍ Scribed by Ivan Vokřál; Robert Jirásko; Veronika Jedličková; Hana Bártíková; Lenka Skálová; Jiří Lamka; Michal Holčapek; Barbora Szotáková

Book ID: 113945306
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 375 KB
Volume: 185
Category: Article
ISSN: 0304-4017
DOI: 10.1016/j.vetpar.2011.09.026

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The specific activities of the alkaline phosphatase (APase), type I phosphodiesterase and 5'-nucleotidase activities associated with the brush-border plasma membrane of the tapeworm, Hymenolepis diminuta, decrease significantly as the tapeworm grows and matures. Kinetic analyses of the APase activit