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The in vivo efficacy of phthalocyanine–nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma

✍ Scribed by Monica Camerin; Michela Magaraggia; Marina Soncin; Giulio Jori; Miguel Moreno; Isabelle Chambrier; Michael J. Cook; David A. Russell

Book ID
116430333
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
377 KB
Volume
46
Category
Article
ISSN
0959-8049

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## Abstract A challenge in photodynamic therapy (PDT) is to improve the tumour selectivity of the photosensitizers by using monoclonal antibodies (MAbs). With this aim, we developed MAb‐conjugates with the hydrophobic photosensitizer __meta__‐tetrahydroxyphenylchlorin (__m__THPC) and with the hydro