The in vivo effect of recombinant human granulocyte-colony stimulating factor in neutropenic neonates with sepsis
โ Scribed by Y. Barak; E. Leibovitz; B. Mogilner; A. Juster-Reicher; M. Amitay; A. Ballin; A. Koren; M. Goebel
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 137 KB
- Volume
- 156
- Category
- Article
- ISSN
- 0340-6997
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Combinations of low dosages of purified recombinant human (rh) macrophagecolony stimulating factor (M-CSF; also termed CSF-1) and rh granulocyte-colony stimulating factor (G-CSF) were compared alone and in combination for their influence on the cycling rates and numbers of bone marrow and splenic gr
## Abstract Twenty children 1โ17 (median, 5.5) years of age received GMโCSF during chemotherapyโinduced neutropenia at the dose of 5 ฮผg/kg/day, continued until the absolute neutrophil count (ANC) exceeded 500 ร 10^6^/liter. Twelve children with solid tumors received GMโCSF after courses of conventi
## Abstract Recombinant human granulocyte colonyโstimulating factor (rhGโCSF) and erythropoietin (rhEPO) were used to treat patients with aplastic anemia (AA). In terms of effects on erythrocyte recovery, the combined use of rhGโCSF and rhEPO showed a favorable response in 6 of 14 (42.9%) patients